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Alpha-lipoic acid

Also called: ALA, lipoic acid, R-lipoic acid

An antioxidant your cells use to make energy. It's mainly used to support blood sugar balance and nerve health.

Supplements can interact with medications and aren't right for everyone, especially during pregnancy or breastfeeding, or with a chronic condition. Ask your provider before you start.

Studied for

  • Blood sugar balance
  • Nerve pain and tingling from diabetes (some studies)
  • Antioxidant support
  • Energy and mitochondrial support

Found naturally in

  • Your body makes small amounts
  • Organ meats
  • Spinach
  • Broccoli
  • Potatoes
What variations of alpha-lipoic acid exist?Our top pick, what to skip, and how to read the label

Label red flags

  • 'ALA' on a label can also mean alpha-linolenic acid, an omega-3 fat. Check the full name.

Check with a provider

  • Diabetes, or taking insulin or other medicines that lower blood sugar
  • Taking thyroid medicine, since it may affect thyroid hormone levels
  • Heavy alcohol use or low thiamine (vitamin B1)
  • Pregnancy or breastfeeding
  • In cancer treatment. Ask your oncology team before adding antioxidants.

Supplements that contain it

2 products in Dr. Lesher's dispensary list alpha-lipoic acid on the label.

Dr. Lesher, ND

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Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.

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