Myasthenia gravis
Autoimmune conditionAntibodies block the signal between nerves and muscles, causing weakness that gets worse with use and improves with rest.
For education only — this guide can't diagnose you. If these signs sound familiar, talk with a healthcare provider. Book a consult
What happens
Most people have antibodies against the receptors muscles use to receive nerve signals. Muscles tire quickly, especially those that control the eyes, face, and throat. About 1 in 10 people with myasthenia gravis has a growth on the thymus gland (thymoma).
Who gets it
Before age 40 it's more common in women; after 60 it's more common in men. It often occurs alongside autoimmune thyroid disease.
Signs worth getting checked
- One or both eyelids drooping
- Double vision
- Weakness that's worse later in the day or after activity
- Trouble chewing, swallowing, or speaking clearly
- Weak neck, arms, or legs
- Shortness of breath, which can be serious
Labs to ask about
- Acetylcholine receptor and MuSK antibodies
- Nerve and muscle electrical testing (EMG)
- Chest CT to check the thymus
- Thyroid tests
Treatments your doctor may discuss
- Medicine that strengthens the nerve-to-muscle signal (pyridostigmine)
- Steroids and immune-suppressing medicines
- Surgery to remove the thymus for some people
- IVIG, plasma exchange, or newer biologics for flares
Supportive steps to discuss with your provider
- Some medicines and supplements can worsen weakness, including certain antibiotics, beta-blockers, and magnesium. Check every new one with your care team.
- Plan rest around the times you need your strength most.
- Treat infections promptly. They can trigger flares.
See a doctor promptly if you have
- Trouble breathing or swallowing: call 911 (possible myasthenic crisis)
- Weakness that's getting worse quickly
- New double vision or drooping eyelids
Related conditions
Ready to find the root cause?
Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.