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Saffron

Also called: Crocus sativus, affron, Satiereal

The spice from the crocus flower, studied as an extract for low mood, PMS, and stress. Results so far are promising but come from fairly small studies.

Supplements can interact with medications and aren't right for everyone, especially during pregnancy or breastfeeding, or with a chronic condition. Ask your provider before you start.

Studied for

  • Low mood (some studies)
  • PMS mood symptoms (some studies)
  • Stress and sleep quality (early research)

Found naturally in

  • Saffron threads used as a spice, in dishes such as paella and risotto
What variations of saffron exist?Our top pick, what to skip, and how to read the label

Label red flags

  • No standardization or branded extract listed
  • Unusually low price, which can mean adulteration

Check with a provider

  • Pregnancy. Amounts above what is used in food may stimulate the uterus.
  • Taking antidepressants or other mood medicines
  • Bipolar disorder
  • Taking blood thinners or blood pressure medicines

Supplements that contain it

2 products in Dr. Lesher's dispensary list saffron on the label.

Check with your provider before taking any of these, especially if you're pregnant or take medications.

Parts of the body it affects

Explore what each area does and the conditions that can affect it.

Illustration of the human brain

Brain & nerves

Your brain, spinal cord, and nerves carry every signal in your body, from movement and sensation to mood and memory.

Illustrations: Servier Medical Art, CC BY 4.0

Dr. Lesher, ND

Ready to find the root cause?

Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.

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