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Glycine
A small amino acid with a calming effect. It's also a main building block of collagen and glutathione.
Supplements can interact with medications and aren't right for everyone, especially during pregnancy or breastfeeding, or with a chronic condition. Ask your provider before you start.
Studied for
- Sleep quality
- Calm and relaxation
- Collagen and connective tissue support
- Glutathione support (often paired with NAC)
Found naturally in
- Your body makes it
- Bone broth and gelatin
- Collagen
- Meat, poultry skin, and fish
Label red flags
- Sleep blends where glycine is a small part of a proprietary mix
Check with a provider
- Pregnancy or breastfeeding (not well studied as a supplement)
- Taking clozapine. Glycine may make it less effective.
- Taking sedatives or sleep medicines
Usually found in sleep formulas, magnesium glycinate, collagen and protein powders. Browse Dr. Lesher's dispensary
Parts of the body it affects
Explore what each area does and the conditions that can affect it.
Illustrations: Servier Medical Art, CC BY 4.0

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Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.
